To be frank, I am still perturbed by quotes in The Washington Post surrounding the secondary analysis of the AREDS2 randomized controlled trial (RCT) which was so aptly summarized by Dr Eric Ciappio yesterday.
While it is entirely correct to say “We don’t know whether these supplements might be beneficial at an earlier age”, the AREDS2 study design and results do not support the statement “A much better bet for all-around brain and heart health is eating foods naturally high in omega-3 fatty acids, such as salmon, flaxseed, and walnuts.” Show me the evidence from RCTs to justify this statement. It doesn’t exist. There aren’t any placebo-controlled RCTs with salmon, flaxseed, or walnuts.
Why recommend eating more fish? Are fish a more sustainable protein source? Or is it because of an inherent property, such as n-3 fatty acids? What about the risk of mercury contamination?