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TalkingNutrition

Providing perspectives on recent research into vitamins and nutritionals

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Oat-beta-glucan, a natural way to maintain a healthy blood cholesterol

By Daniel Raederstorff

 

Numerous clinical studies, meta-analyses and systemic reviews have established that oat beta-glucan lowers plasma low-density-lipoprotein-cholesterol (LDL-C) levels. A meta-analysis by Whitehead et al. 2014 (1) showed that oat beta-glucan at doses of 3 g per day significantly decreases both total cholesterol and LDL-C levels. The outcomes suggest that high viscosity oat beta-glucan can reduce cholesterol, while low viscosity products have no significant effect. The physicochemical properties of beta-glucan - notably its molecular weight (MW) and viscosity - are key to the physiological benefits observed with beta-glucan products. The degree of polymerization of the beta-glucan is directly reflected in the viscosity, and the viscosity depends on the molecular weight.

According to a recent survey, over 40% of adults in Europe, Middle East and Africa consider heart health and protection against non-communicable diseases, such as diabetes and cardiovascular diseases, as major health concerns. However, awareness about the vital role that a healthy diet plays in helping to prevent and maintain heart health is relatively high (2). Health authorities in Europe, the US and Canada have approved health claims for the cholesterol-lowering effect of oat beta-glucan at a dose of at least 3 g per day.

Wolver et al. 2016 (3) recently published a paper on the effect of oat beta-glucan on LDL-C in humans with serum LDL-C levels lower than 160 mg/dL. To date, published human studies have demonstrated the effects in a variety of individuals with different baseline LDL cholesterol levels. These mostly range from slightly elevated, or borderline high, to high LDL-C (100 mg/dL to above 190 mg/dL). LDL-C is one of the major risk factors in the development of atherosclerosis. Achieving a LDL-C value of less than 100 mg/dL is especially important in patients who have additional risk factors that could accelerate the development of cardiovascular diseases. There is a clear need to evaluate more closely the effect of oat beta-glucan in healthy individuals with LDL-C levels below 160 mg per day.

The new study reanalyzed the results of a previously published large clinical trial, in which subjects were randomly assigned to receive a breakfast cereal containing 3 g high-MW (3H), 4 g medium-MW (4M), 3 g medium-MW (3M) or 4 g low-MW (4L) oat beta-glucan or a wheat-bran control (W) for four weeks. In subjects with LDL-C <160 mg/dL, daily intake of either 3 g high-MW (MW 2,200,000 g/mol) or 4 g medium-MW (850,000 g/mol) oat beta-glucan significantly decreased LDL-C compared to the wheat bran control by about 7 to 8%. On the contrary, neither 3 g medium-MW (530,000 g/mol) nor 4 g low-MW (210,000 g/mol) oat beta-glucan had a significant effect in healthy individuals with LDL-C <160 mg/dL. The findings clearly show that high molecular weight beta-glucan (3 g per day) is able to lower LDL cholesterol in healthy individuals with a near optimal LDL-C level; a MW of at least 850,000 g/mol is required for an optimal effect.

The authors of the paper concluded, “Overall the studies indicate that a dose of at least 3 g per day of oat beta-glucan can significantly lower total cholesterol and LDL-C levels in healthy individuals having a slightly elevated LDL-C levels, but still below 160 mg/dl. Therefore, oat beta-glucan may be useful for healthy individuals with near optimal or borderline high LDL-C levels (100 to 160 mg/dL) to help them to bring or maintain their LDL-C levels at an optimal level.”

  • Learn more about the health benefits of oat beta-glucan and download the whitepaper HERE
  • “Trends in health concerns across Europe, Middle East and Africa” – download the whitepaper HERE

 

 


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It is for the first time I am getting to hear about the importance of oat beta glucan in maintaining the healthy blood cholesterol level in the body. Healthy diet is so important in maintaining the proper functioning of the heart and prevents from issues like attacks.
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Your body needs some cholesterol to make hormones, vitamin D, and substances that assistance you process sustenances. Your body makes all the cholesterol it needs. Be that as it may, cholesterol likewise is found in a portion of the nourishments you eat cholesterol goes through your circulation system in little bundles called lipoproteins (lip-o-PRO-adolescents). These bundles are made of fat (lipid) within and proteins on the outside.Two sorts of lipoproteins convey cholesterol all through your body: low-thickness lipoproteins (LDL) and high-thickness lipoproteins (HDL). Having solid levels of the two sorts of lipoproteins is vital.
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Various clinical investigations, meta-examinations, and foundational audits have set up that oat beta-glucan brings down plasma low-thickness lipoprotein-cholesterol (LDL-C) levels. A meta-examination by Whitehead et al. 2014 (1) demonstrated that oat beta-glucan at measurements of 3 g for every day altogether diminishes both aggregate cholesterol and LDL-C levels. The results recommend that high consistency oat beta-glucan can decrease cholesterol,
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