DSM's bio solutions for microbial fermentation

Improve your microorganism production

We use High-Throughput Screening (HTS) and our unique PlugBug® expression platform to produce a wide variety of microbial strains optimized for mass-production.

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To achieve high-quality microorganism production you need predictable upscaling with high expression levels and minimal impurities.

We can help you achieve strain improvement and successful scale-up from lab to mass production, in a single step – for a wide variety of species.

Metabolite

We employ HTS to quickly assess the vast numbers of microbial strains produced by random mutagenesis for improved strains – so-called classical strain development. More>

Proteins

We use an expression platform called PlugBug® - so-called because we simply “plug” the recombinant DNA encoding for your protein into our “bugs” -  guaranteeing the highest possible expression rate.

We call the resultant “elite corps” of fungi and bacteria our PlugBugs® - all proven for high-level protein production in large-scale fermentation. They include: Escherichia coli, Bacillus Subtilis, Pichia Pastoris, Kluyveromyces Lactis, Aspergillus Niger. More>

Other microorganisms

Our track record of successful production extends to many other species, including:

Bacteria: various species of Bacillus, Actinomycete, Lactobacillus, and Lactococcus

Fungi: Saccharomyces cerevisiae, Yarrowia lipolytica,  Mortierella alpina, Penicillium chrysogenum, Trichoderma reesei.

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