7-amino-deacetoxycephalosporanic acid (7-ADCA)

Characteristics:
A crystalline powder manufactured via a fermentative process or by an enzymatic process starting from penicillin G potassium.

Application:
The product is used as an intermediate for the manufacture of semi-synthetic cephalosporins.

Therapeutical category:
Not applicable.

Pharmacopoeia quality:
Not applicable.

Regulatory Information:
USA: FDA

Packaging & Shipping: 

FIBC:
Quantity per package: 200 kg, 220 kg, 380kg, 400kg
Approx gross weigth per pallet: add 25kgs to packaging quantity.

FIBC with sewn-in polyethylene liner, in a carton box, one box on a pallet
carton box l x w x h = 120 x 100 x 80 cm 
pallet loaded size l x w x h = 120 x 100 x 95 cm

Appearance:
white or almost white crystalline powder  

Content (HPLC):
"as is":
97.0 - 101.0%  

Delta2 7-ADCA:
≤ 0.3%  

benzyldeacetoxycephalosporanic acid:
not applicable

Absorbance at 425 nm:
(10% w/v solution in 2 N HCl after filtration, measured in a 1 cm cell)
≤ 0.250

Loss on drying:
≤ 0.5%  

Shelf-life:
not applicable; re-test period 18 months

Storage conditions:
below 25 °C, protected from light and moisture