The production processes of DSMPureActives hardly make use of solvents and contain very few process steps compared to the chemical processes.
Abolishment of solvents
The most important improvement from sustainability point of view is the abolishment of the use of aggressive solvents. In the old process, these solvents were necessary during the reaction and to purify the product after the reaction. In the new process, enzymes are used to couple the side chain to the 6-APA or 7-ADCA molecule and all this occurs without using solvents or aqueous media.
Less process steps
Another environmental improvement can be assigned to the reduction in process steps. As a rule of thumb you can say that every process step requires energy and other auxiliaries. The less steps a process is built up of, the less the burden on the environment. Thanks to the enzymatic process, the number of process steps can be drastically reduced. For Cephalexin the number of steps has been reduced with more than 50%.