Functions: Riboflavin is vital for the release of energy from foods and
for healthy skin, eyes and growth. It plays a major role in oxidation and
reduction processes in cells.
Deficiency: Deficiency is rare, and usually occurs in combination with
deficiencies of other water-soluble vitamins. Since cereals are poor sources
of vitamin B2, virtually all types of compound animal feed must contain
vitamin B2 supplements. In farm animals, even marginal vitamin B2 deficiency
leads to loss of appetite and impaired growth rate. Riboflavin deficiency also
affects the nervous system, gastrointestinal tract and reproductive organs. To
prevent deficiency, most feed mixes (except those intended for ruminants) are
fortified with riboflavin.
Production: DSM riboflavin is now produced by a new fermentation
technology using a genetically modified micro-organism, combined with a
stringent purification process. After completion of the fermentation process,
the biomass is destroyed and removed. This intermediate product is then
dissolved and further purified by a combined adsorption and membrane
filtration process. The resulting compound remains chemically identical and is
free of any detectable DNA. The final crystal structure is achieved using
DSM's unique and patent-protected crystallization process, followed by an
advanced drying process. The new crystalline modification leads to the
outstanding properties of the product.
Product forms: Vitamin B2 is available from DSM Nutritional Products as
riboflavin and as riboflavin 5'-phosphate sodium for food and pharmaceutical
applications, and as a spray-dried powder form for animal nutrition.