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Folic acid

Sources: Folic acid belongs to the group of B vitamins and is found primarily in leafy green vegetables, oranges, fortified cereals, wholemeal bread, liver and potatoes. Folic acid was the first member of a class of compounds to be discovered, and the name is still used for the whole group, also known collectively as folates or folacin.

Below: A microscopic picture of folic acid

Functions: Folic acid is vital for healthy blood cells, the formation of new body cells and for healthy growth. It plays an important role in the metabolism of desoxyribonucleic acid (DNA) and ribonucleic acid (RNA), the carriers of genetic information in all living things.

Deficiency: Folic acid deficiency may be the consequence of disease or treatment with certain drugs and may also occur during pregnancy. Abnormalities in the production of blood cells are the main clinical sign of deficiency. The hematological changes associated with folic acid deficiency are similar to those encountered in vitamin B12 deficiency, and patients are often deficient in both vitamins. Folic acid reduces the risk of neural tube birth defects when consumed in adequate amounts by women before and during early pregnancy. For this reason, the enrichment of cereal products with folic acid is compulsory in the USA. Folic acid is easily destroyed during prolonged storage and up to 50% can be lost during cooking. In animals, folic acid deficiency results in anaemia and impaired reproduction, and bad feathering and reduced laying performance and hatchability in poultry.

Product forms: DSM Nutritional Products supplies folic acid as a pure crystalline powder and in a spray-dried form for animal nutrition.

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