Pantothenic acid concentrations in liver are reduced during deficiency. Liver is hypertrophied, and it varies in color from faint yellow to dirty yellow. Nerves and fibers of the spinal cord show myelin degeneration. These degenerating fibers occur in all segments of the cord down to the lumbar region (Scott et al., 1982).
In young chicks, deficiency signs of pantothenic acid deficiency are difficult to differentiate from biotin deficiency–both causing severe dermatitis, broken feathers, perosis, poor growth and mortality. In pantothenic acid deficiency, dermatitis of the feet is evident over the toes, in contrast to biotin deficiency, which primarily affects the foot pads and is often more severe than deficiency of pantothenic acid.
Signs of pantothenic acid deficiency in young turkeys, which are similar to those in young chickens, include general weakness, dermatitis and sticking together of eyelids (Illus. 2). Young ducks do not show the signs usually seen in chickens and turkeys except for retarded growth; however, their mortality rate is very high. Poor feathering is the most prevalent deficiency sign in pheasants and quail (Scott et al., 1964).