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ChiraliTree

DSM Pharma Chemicals, a world leader in chiral technologies, provides access to a broad range of chiral building blocks and intermediates collectively known as ChiraliTree®.

ChiraliTree® is our approach for bringing together all of our expertise and resources in chiral technology. With ChiraliTree® we provide the industry rapid access to chiral building blocks used in the production of complex pharmaceutical intermediates.

Utilizing our innovative technologies, new chiral building blocks are continuously being developed and produced. Some of these building blocks are derivatives of specific unnatural amino acids, such as the (R) and (S) tert-leucine “tree.”

Other Technologies

Crystallization-induced asymmetric transformation employs a combination of stereoselective crystalization with in situ racemisation.

Chirality transfer is the use of one chiral center to influence the creation of additional chiral centers.

Dynamic kinetic resolution combines stereoselective enzymatic resolution with in situ homogeneous metal-catalyzed racemisation.

A range of biocatalytic and homogenous catalytic reactions.

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