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Fermentation Technology

DSM Pharma Chemicals is a global provider of high quality fermentation manufacturing services for the pharmaceutical and biopharmaceutical industries. We provide an array of custom contract manufacturing capabilities with a staff experienced in handling a variety of cell production systems, processing techniques and product types.

Our competencies include strain sourcing, construction, improvement, process development, process scale-up, and the production of secondary metabolites and recombinant proteins. With pluGBug® technology, we enable the rapid scaleup of a strain for commercial applications.

From strain development to launch, DSM focuses the right resources to provide the highest level of service and quality while applying innovative solutions to meet your unique manufacturing needs.

Process Technologies and Capabilities

► Strain development optimization

► Strain production

► Process development

► Down/up scaling

► Downstream processing

► Chemical modification

► Enzymatic modification

► cGMP manufacturing from 3 m3 to 35 m3

Manufacturing Facilities

Pilot plant - Delft, The Netherlands

Commercial production - Capua, Italy

 ► Up to class 10,000 cleanrooms

 ► FDA approved

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