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Mammalian Cell Culture

Mammalian Cell Culture, Monoclonal Antibodies and Recombinant Proteins

DSM Biologics, a unit of DSM Pharmaceutical Products, is a leading provider of manufacturing technology and services to the biopharmaceutical industry. In addition to offering world-class manufacturing services, DSM Biologics has coexclusive rights, along with Dutch biotech company Crucell N.V., to license the high-producing PER.C6® human cell line as a production platform for recombinant proteins and monoclonal antibodies. DSM Biologics’ FDA-approved facility in Groningen, The Netherlands was established in 1986, and has a strong track record for using a broad range of cell lines (PER.C6®, CHO, hybridoma, etc.) in biopharmaceutical manufacturing. In addition, this site has a wide range of experience using multiple manufacturing (batch, fed-batch and continuous perfusion) and purification techniques.

The combination of the PER.C6® human cell line with DSM’s manufacturing services provides companies with a turn-key biologic manufacturing solution that reduces cost, risk and time to market.

Whether you’re poised for preclinical development, clinical trials or commercial production, our staff of scientists and researchers can utilize our manufacturing facilities to bring your project from concept to completion successfully, and ahead of the competition.

Capabilities

► PER.C6® manufacturing platform

► Preclinical, clinical and cGMP commercial manufacturing

► Batch, fed-batch and continuous perfusion

► Process development, optimization and scale up

► Downstream processing

► Process validation

► Purification chromatography

► Analytical development

► Fill and finish services

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