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PER.C6®

PER.C6 and DSM

The PERCIVIA PER.C6® Development Center (Cambridge, Massachusetts, United States), the joint venture of Crucell N.V. (NYSE Euronext, NASDAQ: CRXL; Swiss Exchange: CRX) and Royal DSM N.V. is now Percivia LLC . This new legal structure was established to transform the company from a development center jointly directed by Crucell and DSM into a fully independent biopharmaceutical company focused on the development of PER.C6®-based biobetter proteins and monoclonal antibodies as well as global licensing of the PER.C6® human cell line for production of third party monoclonal antibodies and other proteins.

DSM and Crucell announce expansion of PERCIVIA PER.C6® biopharmaceutical joint venture (22 Sept 2010)

PER.C6® Technology Advantages

  • Human-like glycosylation
  • Rapid development
  • Regulatory acceptance (BMF)
  • High yields

The combination of the PER.C6® human cell line and DSM’s manufacturing services and high-yielding upstream and process step-reducing downstream technologies provides companies with biologic manufacturing solutions help you to reduce cost, risk and time to market.

High Yields

  • 8 grams per liter in fed-batch with standard lgG
  • 27 grams per liter in XD® with standard lgG




PER.C6® is a registered trademark of Crucell Holland B.V.
XD® is a trademark of DSM N.V.

Download our Biologics Brochure

Learn more about our Groningen facility

DSM`s proprietary XD® technology

View our facility video of Groningen, The Netherlands


Karen King
President and Business Unit Director, DSM Biologics
View Video ''Optimized Technologies''


DSM Biologics and Crucell Biologics produced Use of Human Cells for Manufacturing Human Therapeutics webinar with Genetic Engineering & Biotechnology News.
View On Demand 

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