Route Scouting Services – Success Stories

Non-animal derived biocatalysts: pharmaPLE®

• Safe; non-animal origin
• Reproducible; no batch to batch variations
• Scalable; available and implemented at ton scale
• Enzyme engineering; excellent activity, stability as well as regio- and stereoselectivity
• Find out more in the press release or presentation
  

Sustainable route design: from a 7 to 3 step synthesis route

• Reduction of synthesis steps by route scouting
• Identification of suited enzyme
• Unique combination of biocatalysis and copper catalysis
• Reduction of environmental impact illustrated by life cycle assessment for the 1st and 2nd generation route
• Find out more in the article and press release
  
  

Implementation of a safe and clean nitration reaction using DSM’s micro reactor technology

• Safe & clean; strict controlled reaction conditions, efficient heat transfer and limited residence time of unstable materials
• Design; the micro reactor system combines three key process steps (the nitration reaction, neutralization, and work up)
• Scalable; available and implemented at ton scale under cGMP
• Find out more in the article or see the webinar