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Commercial Manufacturing

Commercialization of your project will receive the lift it needs through our worldwide manufacturing footprint with its global reach and comprehensive tech transfer capabilities. Our strengths can be shared across the spectrum of pharmaceutical and biopharmaceutical custom manufacturing services ensuring you receive what you need, when you need it, and on time to market.

For our biopharmaceutical customers, our Groningen, Netherlandsmanufacturing facility offers the scope and infrastructure necessary to meet your needs. Whether you’re delivering monoclonal antibodies or proteins, Groningen has the integrated approach to biopharmaceutical production that guarantees a quality product.

At our Venlo, The Netherlands facility our research and development teams and manufacturing staff bring you a breadth manufacturing services in the pharmaceutical and biopharmaceutical arena. Our menu includes chiral synthesis, biocatalysis, Grignard reactions, Friedel & Crafts reactions, bromination, chlorination, aromatic substitutions, metal hydride reductions.  A part of DSM since 1987, the facility offers customers a state-of-the-art production and pilot plant, a biological waste water treatment plant, off-gas incineration, and an R&D and pilot plant. Through 44 reactors, Venlo is able to deliver total reactor volume of 176 m³.

Our commercial capabilities within the pharma chemicals arena extends even further through our Linz, Austria facility. Offering a customers a broad choice of manufacturing capabilities our types of plants include:  multipurpose plants, multiproduct ozonolysis plant, glyoxylic acid plants and an esterfification plant. Additional facilities include R&D, (cGMP) Pilot Plant and Engineering at site, ISO 9001 approved MP facilities, Biological waste water treatment and modern high shelf storage. Formerly Chemie Linz, Linz has been part of DSM since 1996.

In the United States, our Greenville, North Carolinafacility drives our services in the sterile fill finish and orals and topicals environments.  A premier facility of DSM, Greenville offers customers manufacturing services including hydrogenation, metal hydride reductions, organometallic reactions bromination, chlorination, substitution, sodium azide chemistry, asymmetric catalytic reductions, Heck, Grignard and organolithium reactions. Former Glaxo Wellcome site, Greenville has been part of DSM since 2000 and include three cGMP, multipurpose plants (10 production trains), a hydrogenation plant, an R&D and pilot plant, FDA approved multi purpose facilities, waste water treatment plant and 5 incinerators. Greenville offers customers 61 reactors with a total reactor volume of 185 m³.

DSM's Greenville, North Carolina facility

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