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Homogeneous Catalysis

High Throughput Screening (HTS)

For application of homogeneous catalysis in the production of fine chemicals speed of development is essential. For this reason we have built a strong capability in the area of high throughput screening. Our robots are standardly used in screening for the best catalyst and the subsequent optimization process. Reaction conditions range from -40º to 150ºC and from atmospheric pressure to high pressure (30 bar). High throughput analysis is available, using HPLC (including chiral HPLC), GC and flow NMR.

Cover picture of European Journal of Organic Chemistry, containing the DSM review article on High Throughput Experimentation for Homogeneous Catalysis Research in Fine Chemicals.
Eur. J. Org. Chem., 2003, 799-811

Chemical Competences

Biocatalysis
Homogeneous Catalysis
Chirality
Amino Acids
Oxidation
Special Reagents
Fermentation

Homogeneous Catalysis:

Asymmetric homogeneous cat.
Aromatic substitutions
C-C bond formation
High throughput screening

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