DSM Biologics, a business unit of DSM Pharmaceutical Products (headquartered in Parsippany, NJ) and Crucell (headquartered in Leiden, Netherlands) have signed a Biopharmaceutical Manufacturing Agreement for production on the basis of the PER.C6® manufacturing platform of Crucell’s proprietary antibody cocktail (containing two antibodies), which Crucell develops against rabies. Under the terms of the agreement, Crucell has contracted DSM Biologics, its alliance partner for the PER.C6® manufacturing platform, for the process validation and manufacturing of antibody batches for Phase III clinical efficacy studies. The services will be provided out of DSM Biologics’ FDA-approved manufacturing facility in Groningen, The Netherlands.

“DSM Biologics is very pleased to be involved in this exciting project. The agreement is a clear recognition of the value that the PER.C6® manufacturing platform brings to the biopharmaceutical industry” says Karen King, President, DSM Biologics.

About the PER.C6® Technology Platform
Crucell's and DSM’s PER.C6® technology platform has been developed for the large-scale manufacture of biopharmaceutical products including vaccines. Compared to conventional production technologies, the strengths of the PER.C6® technology lie in its excellent safety profile, scalability and productivity under serum-free culture conditions.

About DSM Biologics
DSM Biologics, a business unit of DSM Pharmaceutical Products, is a global provider of manufacturing technology & services to the biopharmaceutical industry. In addition to offering world-class biopharmaceutical manufacturing services, DSM Biologics has co-exclusive rights, along with Dutch biotech company Crucell N.V., to license the high-producing PER.C6® human cell line as a production platform for recombinant proteins and monoclonal antibodies. The combination of the PER.C6® human cell line and DSM’s manufacturing services provides companies with a turn-key biologic manufacturing solution reducing cost, risk and time to market.