DSM Biologics and MorphoSys AG (Frankfurt Stock Exchange: MOR; Prime Standard
Segment, TecDAX) today announced the signing of a Biopharmaceutical
Manufacturing Agreement covering process development and cGMP manufacturing of
MOR202. MOR202 is a fully human HuCAL® antibody, directed against CD38, a
promising target for the treatment of multiple myeloma. DSM Biologics will
manufacture MOR202 in its cGMP facilities in Groningen, the Netherlands.
Further financial details on this agreement were not disclosed.
“Based on the positive experiences we have gained with the PER.C6® cell line
and DSM's manufacturing capabilities within our MOR103 lead program, we have
chosen to continue to use this platform for MOR202." commented Dr. Marlies
Sproll, Chief Scientific Officer of MorphoSys.
“We are very pleased that MorphoSys is extending its business partnership with
DSM Biologics as their preferred manufacturing partner after our highly
successful collaboration on the MOR103 program.” says Marcel Lubben, VP
Marketing & Sales at DSM Biologics. “It is exciting how well the combination
of our two strong platforms works for fully human antibodies.” Lubben added.
About PER.C6® Technology
Crucell's PER.C6® technology
platform has been developed for the large-scale manufacture of
biopharmaceutical products such as recombinant proteins including monoclonal
antibodies. Compared to conventional production technologies, the strengths of
PER.C6® technology lie in its excellent safety profile, scalability and
productivity under serum-free culture conditions.
About
DSM Biologics
DSM Biologics, a business unit of DSM Pharmaceutical
Products, is a leading provider of manufacturing technology & services to the
biopharmaceutical industry. In addition to offering world-class
biopharmaceutical manufacturing services, DSM Biologics has co-exclusive
rights, along with Dutch biotech company Crucell N.V., to license the
high-producing PER.C6® human cell line as a production platform for
recombinant proteins and monoclonal antibodies. DSM Biologics’ FDA-approved
facility in Groningen, the Netherlands was established in 1986, and has a
strong track record in using a broad range of cell lines (PER.C6®, CHO,
hybridoma, etc.) in biopharmaceutical manufacturing, and has a wide-range of
experience using multiple manufacturing (batch, fed-batch and continuous
perfusion) and purification techniques. The combination of the PER.C6® human
cell line and DSM’s manufacturing services provides companies with a turn-key
biologic manufacturing solution reducing cost, risk and time to market. For
more information, please visit
www.dsmbiologics.com.
About DSM Pharmaceutical Products
DSM Pharmaceutical Products
is a global provider of high quality custom contract manufacturing and
development services to the pharmaceutical and biopharmaceutical industries.
DSM Pharmaceutical Products contract manufacturing services including:
chemical development, registered intermediates and starting materials, active
ingredients (API's), mammalian cell production of monoclonal antibodies and
proteins, formulation development, Clinical trial manufacturing and finished
dose form manufacturing of solids, semi-solids, and scheduled drugs, aseptic
liquid and lyophilized products.
DSM – the Life Sciences and Materials Sciences Company
DSM creates innovative products and services in Life Sciences and Materials
Sciences that contribute to the quality of life. DSM’s products and services
are used globally in a wide range of markets and applications, supporting a
healthier, more sustainable and more enjoyable way of life. End markets
include human and animal nutrition and health, personal care, pharmaceuticals,
automotive, coatings and paint, electrics and electronics, life protection and
housing. DSM has annual sales of almost EUR 8.8 billion and employs some
23,000 people worldwide. The company is headquartered in the Netherlands, with
locations on five continents. DSM is listed on Euronext Amsterdam.