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DSM Biologics and Crucell Announce PER.C6® Licensing Agreement with Sartorius Biotech GmbH
Sittard/Leiden,NL,05-Jun-2007

DSM Biologics, a business unit of DSM Pharmaceutical Products and Dutch biotechnology company Crucell N.V. (Euronext, NASDAQ: CRXL; Swiss Exchange: CRX) today announced a non-exclusive PER.C6® research licensing deal with Goettingen, Germany-based Sartorius Biotech GmbH. Sartorius will use Crucell’s key technology to evaluate monoclonal antibodies produced using PER.C6® cells for calibrating and testing equipment products useful in the manufacture and/or purification of recombinant monoclonal antibodies. Crucell and Sartorius further agreed to expand their PER.C6® collaboration by sharing technology and data on antibody production. Financial details were not disclosed.

About the PER.C6® Technology Platform
Crucell's and DSM’s PER.C6® technology platform has been developed for the large-scale manufacture of biopharmaceutical products including vaccines. Compared to conventional production technologies, the strengths of the PER.C6® technology lie in its excellent safety profile, scalability and productivity under serum-free culture conditions.

About Crucell
Crucell N.V. (Euronext, NASDAQ: CRXL; Swiss Exchange: CRX) is a biotechnology company focused on research, development and worldwide marketing of vaccines and antibodies that prevent and treat infectious diseases. Its vaccines are sold in public and private markets worldwide. Crucell’s core portfolio includes a vaccine against hepatitis B, a fully-liquid vaccine against five important childhood diseases, and a virosome-adjuvanted vaccine against influenza. Crucell also markets travel vaccines, such as the only oral anti-typhoid vaccine, an oral cholera vaccine and the only aluminum-free hepatitis A vaccine on the market. The Company has a broad development pipeline, with several Crucell products based on its unique PER.C6® production technology. The Company licenses this and other technologies to the biopharmaceutical industry. Important partners and licensees include DSM Biologics, sanofi aventis, GSK and Merck & Co. Crucell is headquartered in Leiden (the Netherlands), with subsidiaries in Switzerland, Spain, Italy, Sweden, Korea and the US. The Company employs over a 1000 people. For more information, please visit www.crucell.com.

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For more information
DSM Pharmaceutical Products
+1 973 257 8471
Terry.Novak@dsm.com
DSM Biologics
+31 46 47 73343
Marcel-m.lubben@dsm.com
Crucell N.V.
+31-(0)71-524 8722
Leonard.Kruimer@crucell.com
Barbara Mulder
+31715197346
barbara.mulder@crucell.com
Crucell N.V. in the USA
+1 212 926 1733
tredington@redingtoninc.com
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