Skin Bioactives

Revealing the power of ultimate skin appearance and sensation

DSM capitalizes on its more than 40 years of expertise in skin biology to translate scientific findings into tangible consumer benefits in many areas of skin care. Today our broad portfolio of skin actives and bioactive skin care ingredients includes synthetic peptides, organically grown plant extracts and other natural ingredients, and vitamins for cosmetic applications.

Skin Bioactives

  • ALL-Q Plus

    ALL-Q Plus

    ALL-Q Plus is a bioactive mix of coenzyme Q10 and vitamin E acetate in a cosmetic carrier oil. ALL-Q Plus is the ideal active ingredient for several key applications such as skin protection formulations (sun care, environmental stress) and others.

  • ALLANTOIN

    ALLANTOIN

    ALLANTOIN is an effective bioactive ingredient used in a wide range of personal care formulations. Allantoin improves skin moisture retention providing a skin smoothing effect.

  • ALPAFLOR® -ALP-SEBUM CB

    ALPAFLOR® -ALP-SEBUM CB

    ALPAFLOR® -ALP-SEBUM CB is an organic bioactive rich in flavanoids and oenothein B - key compounds that show sebum-regulating and anti-inflammatory activities. It is COSMOS and NATRUE organic certified and Fair for Life fair trade certified.

  • ALPAFLOR® ARTEMISIA AO

    ALPAFLOR® ARTEMISIA AO

    ALPAFLOR® ARTEMISIA AO is a natural, organic plant extract Artemisia umbelliformis, is rich in phenolic acids, tannins and flavonoids and is therefore a great natural, sustainable bioactive for anti-oxidative cosmetics. Proven in-vitro protective anti-oxidative efficacy, this alpine extract is suitable for any skin care formulation. This bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® BUDDLEJA AO

    ALPAFLOR® BUDDLEJA AO

    ALPAFLOR® BUDDLEJA AO is an organic, sustainable active extract from Buddleja davidii. Rich in phenylethanoids, flavonoids, and iridoids, this alpine extract is the active ingredient to help prevent the appearance of aging. This bioactive ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® EDELWEISS CB

    ALPAFLOR® EDELWEISS CB

    ALPAFLOR® EDELWEISS CB is an organic bioactive that protects skin barrier, enhances skin resistance to external stress factors and provides an ultimate skin sensation. It is COSMOS and NATRUE organic certified and Fair for Life fair trade certified.

  • ALPAFLOR® GIGAWHITE CB

    ALPAFLOR® GIGAWHITE CB

    ALPAFLOR® GIGAWHITE CB is a complex of 7 Swiss alpine plant extracts. It is a radiant skin bioactive that keeps the skin at its luminous best. The main active ingredients are flavonoids, phenolic acids, polysaccharides, and iridoids. It is COSMOS and NATRUE organic certified and Fair for Life fair trade certified.

  • ALPAFLOR® IMPERATORIA AO

    ALPAFLOR® IMPERATORIA AO

    ALPAFLOR® IMPERATORIA AO is a sustainable alpine plant extract of Peucedanum ostruthium. This organic extract is the ideal active ingredient for all types of skin regenerating formulations. This bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life Fair Trade certified.

  • ALPAFLOR® LINUM AO

    ALPAFLOR® LINUM AO

    ALPAFLOR® LINUM AO is a sustainable alpine plant extract of Linum alpinum. With its capacity to reduce the ICAM-1 expression induced by inflammatory cytokines, this natural, organic extract demonstrates calming properties for sensitive, irritated, and dry skin, proven in vitro. This bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® MALVA AO

    ALPAFLOR® MALVA AO

    ALPAFLOR® MALVA AO is an organic, sustainable plant extract of Malva sylvestris. The bioactive is rich in mucilages, polysaccharides, and tannins, therefore provides moisturizing and soothing care for sensitive skin. This bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® MARRUBIUM AO

    ALPAFLOR® MARRUBIUM AO

    ALPAFLOR® MARRUBIUM AO is an organic, sustainable plant extract from Marrubium vulgare. Proven in vitro to reduce histamine production, this alpine extract protects skin against reactions induced by UV radiation and relieves irritated and stressed skin. The bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® NECTAPURE PF

    ALPAFLOR® NECTAPURE PF

    ALPAFLOR® NECTAPURE PF is a mix of organic, sustainable plant extracts from Buddleja davidii and Thymus vulgaris. In-vitro proven protective effect against ozone and in-vivo demonstrated moisturizing properties, this alpine extract is the ideal active ingredient antipollution formulations. The bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® SAMBUCUS AO

    ALPAFLOR® SAMBUCUS AO

    ALPAFLOR® SAMBUCUS AO is an organic, sustainable plant extract from Sambucus nigra. Proven in vitro to reduce VEGF biosynthesis, this alpine extract is the ideal active ingredient for all types of formulations to protect against the appearance of puffiness and heavy legs. The bioactive is ECOCERT, COSMOS, and NATRUE organic certified, and Fair for Life fair trade certified.

  • ALPAFLOR® SCUTELLARIA CB

    ALPAFLOR® SCUTELLARIA CB

    ALPAFLOR® SCUTELLARIA CB is an organic bioactive fighting urban stress and leaving the skin soothed, radiant and feeling relaxed. This ingredient is COSMOS and NATRUE organic certified and Fair for Life fair trade certified.

  • ALPHA-ARBUTIN

    ALPHA-ARBUTIN

    ALPHA-ARBUTIN is a superior skin care ingredient for an even skin tone. It reduces the degree of skin tanning after UV exposure and helps to minimize the appearance of liver spots.

  • Argan oil

    Argan oil

    Argan oil is a natural, organic skin bioactive obtained from the kernels of the endemic argan tree (Argania Spinosa kernel oil). This bioactive ingredient is ECOCERT, COSMOS and NATRUE organic certified.

  • BEL-EVEN®

    BEL-EVEN®

    The innovative cosmetic ingredient BEL-EVEN® locally rebalances the negative, long-term effects of stress on skin and fights against stress-induced collagen loss and skin thinning.

  • CEPHALIPIN NP2

    CEPHALIPIN NP2

    CEPHALIPIN NP2 is a botanical skin bioactive helping restore and maintain the natural skin barrier function of the stratum corneum, making it particularly suitable for aftershave formulations.

  • COLHIBIN CB

    COLHIBIN CB

    COLHIBIN CB is a plant-derived skin bioactive from vegetable origin. This skin active has strong MMP (Collagenase) inhibition properties that protect the collagen fibers.

  • COLHIBIN CB

    COLHIBIN CB

    COLHIBIN CB is a plant-derived skin bioactive from vegetable origin. This skin active has strong MMP (Collagenase) inhibition properties that protect the collagen fibers.

  • COLLAGEN

    COLLAGEN

    COLLAGEN 1% is a solution of highly purified, native atelocollagen. It gives a unique skin feel and acts as a water reservoir on the skin, thus helping to promote skin hydration.

  • DISMUTIN® PF

    DISMUTIN® PF

    DISMUTIN® PF is a biotech skin active, highly purified superoxide dismutase (SOD) from Saccharomyces cerevisiae with outstanding anti-inflammatory activity.

  • ELHIBIN® PF

    ELHIBIN® PF

    ELHIBIN® PF is a Chinese listed, bioactive cosmetic ingredient that helps to promote youthful elastic skin conditions and combat the ageing process. 

  • ERYTHRULOSE

    ERYTHRULOSE

    The skincare tanning ingredient ERYTHRULOSE provides you with a beautiful, natural-looking homogenous and glowing skin tone that enriches the appearance of your skin.

  • HYALURONIC ACID-BT

    HYALURONIC ACID-BT

    HYALURONIC ACID-BT is a pure, ECOCERT approved biotechnologically manufactured skin bioactive that perfectly moisturizes skin and improves skin smoothness, elasticity and freshness.

  • HYASOL PF

    HYASOL PF

    HYASOL PF is an aqueous solution of a high molecular mass hyaluron polymer of about 1.6 MDa. The bioactive delivers outstanding tactile experience and skin revival immediately after application.

  • HYDROLASTAN PF

    HYDROLASTAN PF

    HYDROLASTAN PF is a hydrolyzed elastin bioactive providing a natural protein layer of protection against environmental factors, leading to improved elasticity of the skin.

  • Hyaluronic Acid HYA ACT

    Hyaluronic Acid HYA ACT

    This skin microbiome friendly new ingredient line, HYA-ACT™ includes highly efficient hyaluronic acid grades featuring different molecular weights that deliver the efficacy and beauty benefits customers want.

  • IRICALMIN™ PF

    IRICALMIN™ PF

    IRICALMIN™ PF is a biopolymer complex containing wheat germ, yeast extract, sodium hyaluronate, and panthenol. IRICALMIN™ PF relaxes UV-induced skin irritation, enhances regeneration of protective lipids.

  • LIPOGARD

    LIPOGARD

    LIPOGARD is a bioactive mix of coenzyme Q10 and vitamin E acetate in a carrier oil. LIPOGARD restores the lipid barrier and guarantees full cell membrane functionality.

  • Life’s GLA™ 10 N-6 Oil

    Life’s GLA™ 10 N-6 Oil

    Life's GLA™ 10 n-6 Oil is a naturally rich in polyunsaturated fatty acids with a high GLA content. The active contains at least 9% γ-linolenic acid (GLA) in the form of triglycerides and is stabilized with dl-α-tocopherol and ascorbyl palmitate.

  • Life’s GLA™ 25 N-6 Oil

    Life’s GLA™ 25 N-6 Oil

    Life's GLA™ 25 n-6 Oil is a naturally rich in polyunsaturated fatty acids with a high GLA content. The active contains at least 23% γ-linolenic acid (GLA) in the form of triglycerides and is stabilized with dl-α-tocopherol and ascorbyl palmitate.

  • OXY 229 CB

    OXY 229 CB

    The postbiotic bioactive to improve the look of tired and dull-looking skin

  • OXY 229 PF

    OXY 229 PF

    New studies on the skin microbiome show that the skincare ingredient OXY 229 PF reduces sebum levels and minimizes Corynebacterium Kroppenstedtii - a novel target for the control of skin redness.

  • PENTACARE HP PF

    PENTACARE HP PF

    PENTACARE HP PF is an effective skin tightening bioactive consisting of a plant-derived polysaccharides and a milk-based protein hydrolysate.

  • PENTACARE NA PF

    PENTACARE NA PF

    PENTACARE-NA PF is a bioactive mix of galactomannanes obtained from seeds of locust bean gum and hydrolyzed proteins isolated from wheat gluten.

  • PENTAGLYCAN PF

    PENTAGLYCAN PF

    PENTAGLYCAN PF is an aqueous bioactive solution of glycosaminoglycans, isolated from cartilaginous fish, and hyaluronic acid. PENTAGLYCAN PF is a marine polysaccharide which imparts lubricity to the skin surface, leading to smooth skin.

  • PENTAVITIN®

    PENTAVITIN®

    The natural moisturizing skincare ingredient PENTAVITIN® provides powerful hydration to all facial areas, visualized by new facial skin hydration color mapping technology.

  • PEPHA® -AGE CB

    PEPHA® -AGE CB

    The natural skin care ingredient PEPHA®-AGE CB stimulates skin’s own defense against the negative impact of blue light protecting the skin barrier and boost the collagen synthesis.

  • PEPHA®-CTIVE CB

    PEPHA®-CTIVE CB

    PEPHA®-CTIVE CB is a biotech ingredient produced from microalgae Dunaliella salina. Thanks to its composition rich in amino acids, minerals, and carbohydrates, PEPHA®-CTIVE CB protects and stimulates mitochondria by increasing ATP levels.

  • PEPHA®-PROTECT

    PEPHA®-PROTECT

    PEPHA®-PROTECT is natural bioactive extracted from watermelon, very rich in vitamins, carbohydrates, and amino acids. It harnesses the action of the watermelon to strengthen the natural defenses of human skin.

  • PEPHA®-TIGHT CB

    PEPHA®-TIGHT CB

    PEPHA®-TIGHT is a unique natural tightening and firming skincare ingredient which delivers both a fast, instant tightening experience, and a superior long-term skin firming effect.

  • PHYTALURONATE® PF

    PHYTALURONATE® PF

    PHYTALURONATE® PF is a natural bioactive from highly purified fraction of branched galactomannan derived from the seeds of the St. John's bread tree.

  • PHYTANTRIOL

    PHYTANTRIOL

    PHYTANTRIOL is a unique active for skin care and hair care applications. Hair care studies demonstrated its efficacy to increase deposition of panthenol, ethyl-panthenol, and keratin amino acids.

  • PREREGEN® PF

    PREREGEN® PF

    PREREGEN® PF is a unique bioactive mix of botanically derived peptides and biotechnologically produced oxido reductases. This unique complex shows free radical neutralization and elastase-inhibiting properties, as well as anti-ozone activity.

  • REGU®-AGE PF

    REGU®-AGE PF

    REGU®-AGE PF is a natural bioactive skincare ingredient that protects the delicate skin around the eyes and visibly reduces the look of dark circles and eye puffiness.

  • REGU®-FADE

    REGU®-FADE

    The skincare ingredient REGU®-FADE is a high-performing, nature-identical resveratrol that visibly brightens skin within two weeks.

  • REGU®-SEB

    REGU®-SEB

    REGU®-SEB is a natural bioactive complex that balances and mattifies oily skin to unveil a natural look, by regulating the production of sebum to a normal level.

  • REGU®-SLIM

    REGU®-SLIM

    REGU®-SLIM is a patented bioactive for body re-shaping smoothing and skin tightening. Demonstrated in vitro and in vivo, to stimulate lipolysis and reduce the appearance of orange-peel skin, REGU®-SLIM is an innovative fat-cell burner and skin smoother.

  • REGU®-STRETCH

    REGU®-STRETCH

    REGU®-STRETCH is a patented bioactive complex that protects the skin structure from new stretch marks, and activates the repair process by stimulating the synthesis of collagen and by reducing skin inflammation.

  • REVITALIN® CB

    REVITALIN® CB

    The bioactive cosmetic ingredient REVITALIN® CB boots the skin's oxygen content and consumption to help provide energized, revitalized skin that looks and feels good.

  • SERICIN

    SERICIN

    SERICIN is a natural silk bioactive extract produced by the silk worm Bombyx mori. The unique silk protein SERICIN has strong affinity to keratin.

  • SETAKOL® PF

    SETAKOL® PF

    SETAKOL® PF is an aqueous bio active solution of the hydrolyzed silk glycoprotein sericin. SETAKOL® PF forms a highly substantive, protective film on the surface of skin and it reduces the irritation caused by surfactants.

  • STIMU-TEX® AS

    STIMU-TEX® AS

    The natural certified skincare ingredient STIMU-TEX® AS visibly reduces histamine-related symptoms like irritation and itching for a truly soothed and flawless looking skin.

  • SYN-EYE®

    SYN-EYE®

    The peptide ingredient SYN-EYE® combines peptide technology with skin bioactives in a multifunctional eye care formula. It visibly reduces the appearance of lines and wrinkles around the eyes.

  • SYN-GLOW®

    SYN-GLOW®

    The peptide ingredient SYN-GLOW® works with skin to bring out its natural healthy glow, all year round as if you are just back from holiday.

  • SYN-STAR®

    SYN-STAR®

    SYN-STAR® -an innovation based on existing patented peptide technology – showed, for the first time, a global anti-ageing and mattifying effect in a study on three different skin tones.

  • SYN-TC®

    SYN-TC®

    SYN-TC® is a cosmetic synthetic peptide ingredient, tailor-made to ensure best performance for high-performing, facial anti-ageing skin care formulations.

  • SYN-UP®

    SYN-UP®

    Our unique peptide cosmetic ingredient SYN-UP® has excellent capacity to fight against dry skin conditions and, skin redness, due to its interaction on two common skin bacteria.

  • SYN®-AKE

    SYN®-AKE

    SYN®-AKE is a small synthetic peptide active ingredient that helps reduce the appearance of wrinkles and laughter lines. It’s fast acting, long lasting and fully reversible.

  • SYN®-COLL

    SYN®-COLL

    SYN®-COLL is a synthetic tripeptide china listed cosmetic ingredient that simultaneously boosts collagen production and protects against collagen degradation.

  • SYN®-HYCAN

    SYN®-HYCAN

    SYN®-HYCAN a patented cosmetic tripeptide ingredient boosts skin’s own renewal of hyaluronic acid, resulting in a visible remodeling effect and firmer, more moisturized skin.

  • SYN®-TACKS

    SYN®-TACKS

    The peptide ingredient SYN®-TACKS increases elasticity, firmness and suppleness by boosting the function of the Dermal-Epidermal Junction (DEJ).

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