The sequencing project was started in June 2000 and has been completed in October 2001. A structured BAC-approach underlies the sequencing project. Summarised in brief, the genomic DNA is chopped into large DNA fragments (BAC's) that are end-sequenced, tiled and subsequently individually sequenced in a random shotgun approach. The project has resulted in a high quality DNA sequence (8x coverage) including ~99% of all the DNA sequences (excluding repetitive regions).
The genome is analysed and annotated in a high quality process. This consists of two phases in which an automatic gene prediction and annotation is followed by a manual correction and verification at the German company Biomax, a collaborator with Gene Alliance.
Access to the Aspergillus genome
DSM realises that the information contained in the Aspergillus niger genome is relevant to several outside parties. In order to meet the outside need for access, DSM has created several possibilities
Licensing
A licensing program has been initiated on the Aspergillus niger DNA sequence for commercial parties. Licenses will be distributed on a non-exclusive basis. Further information on licensing can be obtained via our intellectual asset manager.
Data access to researchers at academic and non-commercial institutions
DSM provides access to the Aspergillus niger database to researchers belonging to non-profit organisations. Please read the Registration for New Users. Each new user will be required to complete the Registration Agreement.
