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DSM Resolve

Biomedical

Analytical sciences for biomedical: At your service

In the Biomedical market we draw on a deep analytical knowledge from Material Sciences – and indeed where it interacts with biological sciences. In turn this is helping customers drive innovation in applications like implants, medical device coatings and drug delivery systems – for example in better understanding the degradation of polymers in medical applications.
meso-bio-matrix

Challenges we solve

We are part of DSM - the leading medical device materials development and manufacturing partner in the world. It’s a field facing rapid changes in the product requirements set by regulatory bodies and consumers; which is where we help customers gain a better understanding of their applications through:

  • Process reliability: Correlating and controlling the quality of base products to the final product quality based on experimentation involving Materials Processing.
  • Product safety: For example, polymeric drug delivery through the detailed profiling of their in-vivo and in-vitro degradation process.
  • Detailed product specifications: With an emphasis on the profound materials characterization applied through our experience in designing validated Macromolecular identification methodologies.

 

Biomedical science competences: What’s in the toolbox?

For this very broad science area, we use all our techniques and technologies to solve customers’ challenges based on our base competences like Molecular Structures, Morphology and Data Analysis & Statistics – which in turn creates our unique capability in fields like Materials & Chemical Processing

Morphology - Electron Microscopy – cryo-wet SEM (VERSA -3D)/EDX, TEM (Osiris), Cryo TEM (UM), STEM-EDX. Xray-Scattering (tensile stage - SAXS, WAXS, XRPD,..), HR Optical Microscopy, Atomic Force Microscopy (Nano-IR), Solid State NMR (400 MHz – Melt probe), QCM, (confocal) Fluorescence Microscopy (UM), XPS (Outsourcing).

Molecular Structure - SS- & L-NMR Spectroscopy (500, 600 & 700 MHz), HT & Meltprobe, FTIR & Raman spectro- & microscopy, UV-VIS microscopy, Fluorescence Microscopy, Ion Mobility Spectrometry, Mass Spectrometry (MS/MS), MALDI/ESI ASAP/EI/DCI, TOF-SIMS (Imaging) & MALDI Imaging

Data analysis & statistics - DoE, White box modelling (reaction kinetics), numerical mathematics, method validation, data mining, chemometry (PLS, PCA), 6-sigma support, image data analysis, algorithm development, tools development (macros in Excel, GUI), Sensometrics.

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