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DSM Biomedical launches new application for ComfortCoat

Geleen, NL, 25 Feb 2009 16:15 CET

Advanced lubricious hydrophilic coating now available, designed to enhance maneuverability of metal guidewires, uncoiled and coiled, in minimally invasive procedures.

DSM Biomedical, a global biomaterials company serving the medtech and biotech industries and a wholly owned subsidiary of Royal DSM N.V., announced today that it has launched a new application for ComfortCoat™, an advanced lubricious hydrophilic coating designed to enhance maneuverability of metal guidewires in minimally invasive procedures. For example, minimally invasive procedures are carried out to treat strokes, brain aneurysms, and other neurovascular diseases.

Metal guidewires are more easily maneuvered within a patient's vasculature when the friction between the walls of the vessel and the intravascular guidewire is reduced by coating the device with a hydrophilic compound that becomes slippery after adsorbing water—for example, when the coated device is exposed to water prior to insertion into a patient or into a patient's blood during use. However, it is important to note that, typically, hydrophilic coatings cannot be applied to metal guidewires because their adhesion to metal is poor, especially in the case of coiled guidewires. With ComfortCoat, adhesion to metal is not a problem; lubricity is maintained on the metal guidewire, which may enhance neurovascular maneuverability.

Of course, the coating on a medical device can make a significant difference in patient care and comfort. Every year, tens of millions of patients undergo procedures involving guidewires and catheters. Uncoated or poorly coated devices can cause trauma to blood vessels and other tissue, and can affect the success of procedures in which they’re used,” said John Marugg, DSM Biomedical’s Business Manager for ComfortCoat.

Our new grade of ComfortCoat is designed to offer several critically important benefits for metal guidewires, including lubricity, durability, abrasion resistance, and biocompatibility,” added Marugg. “The advanced lubricity of ComfortCoat can significantly reduce the friction of medical devices, especially vascular guidewires. This can help surgeons or physicians to better navigate through torturous pathways, occlusions or even-smaller vessels, to reach the areas targeted for treatment—without using too much force.”

ComfortCoat’s highly lubricious coating for metal guidewires is now available to medical device companies for testing and can be used for both coiled and uncoiled guidewires.