DSM FloraGLO® Lutein in a starch-based matrix is more bioavailable than alginate-based matrix Lyc-O-Lutein
In this randomized, double-blind, cross-over study conducted by lead author Dr. Malkananthi Evans and co-authors, the effect of formulation differences on the bioavailability of lutein was evaluated using a starch-matrix FloraGLO® Lutein 5% and a alginate-matrix Lyc-O-Lutein 20%. Forty-eight healthy subjects were given a single dose of 20 mg lutein from either of the two formulations and lutein was measured in the plasma at several time intervals. After a wash out period of 28 days the study was repeated with the alternative formulation. The findings were highly significant. After 14 hours, total plasma lutein increased by 126% with the starch matrix FloraGLO Lutein 5% compared to only 7% with the alginate matrix Lyc-O-Lutein 20%. After 672 hours the area under the curve for total lutein was 1.3-fold higher for the starch-matrix FloraGLO Lutein 5% compared to the alginate-based Lyc-O-Lutein 20%.
The practical application of this study is highly relevant. Although lutein has demonstrated benefits in eye health it can only impart those benefits if this bioactive compound is efficiently absorbed by the body. This study shows that not all lutein sources are equivalent. Their bioavailability clearly depends on the formulation and in this study the starch matrix formulation was much more bioavailable than the alginate matrix utilized in the Lyc-O-Lutein 20% product. The benefits associated with FloraGLO lutein are based on a suite of high quality clinical studies. The above result is a further demonstration that not all brands can deliver these benefits; FloraGLO lutein has proven high bioavailability.
FloraGLO is the world's first patented, purified lutein (www.floraglolutein.com/brochure) brand and is covered by several process and composition patents in a number of geographies worldwide. It is the most clinically researched lutein brand in the world and is selected by leading supplement and food manufacturers for its quality and safety profile. FloraGLO has GRAS (Generally Recognized as Safe) status for several food and beverage applications, and different product forms are available for inclusion into a variety of supplements and foods.
Kemin and DSM Strategic Alliance
In 2008, Kemin and DSM joined forces working under an exclusive strategic alliance. Kemin supplies FloraGLO brand lutein exclusively through DSM, and DSM globally commercializes FloraGLO brand lutein products through distributors and directly to customers. Customers and consumers benefit from the synergies achieved by the collaboration through DSM's global reach, unique formulation technology and broad product portfolio when combined with Kemin's lutein knowledge, intellectual property, technical know-how and market development expertise.
Kemin Industries, Inc. provides 'inspired molecular solutions' specifically developed to provide nutrition and health benefits for humans and animals. Kemin manufactures and markets approximately 500 specialty ingredients to the global feed and food industries as well as the health, nutrition and beauty markets. A privately held, family-owned and operated company, Kemin more than 1,500 employees and operates in 90 countries with manufacturing facilities in Belgium, Brazil, China, India, Italy, Singapore, South Africa and the United states. For more information on Kemin, visit www.kemin.com.
Flora®GLO is a registered trademark of Kemin Industries, Inc.