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DSM in Medical

Breast reconstruction

As a patient, you may have many questions and concerns regarding your options following a mastectomy. One such option is to have your breast(s) reconstructed to restore your sense of well-being. Breast reconstruction is a surgical procedure performed after a mastectomy to restore the size and shape of the breast.

Currently, women may elect to have breast reconstruction with either autologous tissue or with breast implants. It is important to discuss the various options with your plastic surgeon.

How are tissue expanders used in breast reconstruction?

Two-stage, tissue expander assisted breast reconstruction is a common surgical method used to reconstruct the breast. This method either begins immediately after mastectomy (known as immediate breast reconstruction) or at some time afterward (known as delayed breast reconstruction).

During the first stage of the breast reconstruction, the plastic surgeon releases the pectoralis muscle from the chest wall. The tissue expander is implanted partially under the pectoralis and inflated. The tissue expander is gradually filled with saline over several weeks or months, stretching the surrounding tissue. Once the desired breast volume has been achieved, the second stage of the reconstruction takes place. In the second stage, the tissue expander is removed and replaced with a permanent saline or silicone gel breast implant.

How is Meso BioMatrix® Surgical Mesh used with a tissue expander?

After releasing the pectoralis muscle from the chest wall, the surgeon attaches the surgical mesh to the pectoralis muscle and to the chest wall just below the breast. This is done to create a pocket for the tissue expander. The tissue expander is implanted in the pocket and partially inflated.  The Meso BioMatrix® Surgical Mesh is expected to support the weight of the tissue expander, maintain the position of the expander and reinforce the breast pocket.  When the desired breast volume is achieved, the surgeon will replace the tissue expander with a breast implant in a second surgery. Over time, the Meso BioMatrix will integrate into the surrounding tissue.


Female breast images

Breast Reconstruction Clinical Trial

Currently, there are human and animal-derived biologic meshes on the market. However, at present, no surgical mesh device is approved or cleared by the FDA for use in breast reconstruction.

Meso BioMatrix® surgical mesh is currently being evaluated in an FDA approved clinical trial for use in a two-stage, tissue expander assisted breast reconstruction.  Participants in this clinical trial may benefit from the use of this novel product and may contribute to the establishment of an additional option for women considering breast reconstruction.  For additional Information about the clinical trial including eligibility criteria and the location of the participating surgeons, please follow this link to the trial information on

Where can I find additional information on breast reconstruction?

For additional information about the types of breast reconstruction procedures, please visit the American Society of Plastic Surgeons website or the website.