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DSM in Personal Care & Aroma Ingredients


Event details:

23 Oct 2017
End Date:
25 Oct 2017
Seoul, South Korea
In attendance:
IFSCC 2017


The International Federation of Societies of Cosmetic Chemists is a worldwide federation dedicated to international cooperation in cosmetic science and technology. The IFSCC wants to elevate the professional status of cosmetic science and technology worldwide by providing and promoting educational and scientific programs and activities.

Therefore, DSM is proud to be represented with three exciting and innovative poster presentations, to provide a more in-depth insight into some of our scientific capabilities.

See below for a short summary on each of the posters.

The burning question of in-vivo SPF prediction

Why do results from in- vivo and in-vitro SPF testing so often differ, and how can we avoid having to test sunscreens on human beings?

At DSM we’ve been looking at sunscreen film formation in depth, and can now present the design elements needed for an organotypical skin template to enable more accurate in-vivo SPF prediction.

Presentation of poster number P-134 on October 24th at 12.40pm.

Molecular modeling: See skincare targets in 3D!

Molecules within an organism interact with biochemical targets to direct the complex processes in our bodies. Using in silico tools we can now model these interactions in 3D. We modeled the modes of action of 11β-HSD1 inhibition and vitamin D receptor activation as attractive targets for skincare applications.

Presentation of poster number P-196 on October 24th at 12.40pm.

Novel assay targets 11β-HSD1 to combat skin aging

Evidence suggests that 11β-HSD1 is a key skin aging target and topical application of 11β-HSD1 inhibitors may have beneficial effects. Most current test systems for 11β-HSD1 inhibitors use cell lines over-expressing 11β-HSD1 or require radioactive labeled materials. We present a novel in-vitro assay that uses primary human keratinocytes to determine 11β-HSD1 activity. This model is better suited to the field of skincare products, is rapid and radioactive-free.

Presentation of poster number P-068 on October 24th at 12.40pm.