DSM in Pharmaceuticals: Covering the supply chain across the globe

A female pharmacist handing a male customer a bottle of pills

DSM is one of the world’s leading providers of high-quality custom manufacturing services from R&D, to clinical trials, to commercial production and packaging. We’re also one of the major suppliers of active ingredients in bata lactam antibiotics and active ingredients: A staggering 500 million potentially life-saving treatments every year.

In pharmaceuticals the challenges are many: With fewer innovative drugs in the pipeline and stiffer competition, the length of the pipeline itself needs to be shortened. Which means the industry needs to find new efficiencies and explore game-changing innovations like bio-pharmaceuticals. DSM is at the forefront of all these areas and more.

In Pharma Chemicals

Scientist in a laboratory holding a flask containing orange liquidAs one of the world’s leading Contract Manufacturing Organizations, our expertise in complex chemistry is unique in the marketplace whether for tech transfer/commercial production, late or early stage.

In R&D we practice 98% of prevailing chemistries and create many active ingredients and intermediates. In route-scouting and green chemistry our unique convergence of biocatalysis and chemocatalysis (through our Innosyn™ brand) is finding faster routes to new drug compounds with more renewable starter materials.

On the production side our Green Chemistry Toolbox, including Micro Reactors, is increasing productivity - drastically cutting waste and our customers’ carbon footprint.

In Finished dosage

Close up of two pills in a woman's palmWith more drugs than ever coming off patent, there’s a greater need for efficiency and sustainability. We currently fill or freeze-dry two of the top five biotech products on the market and launch an average 25 products every year for our customers.  We also make and package the end product through a wide range of dosage forms including tablets, capsules, ointments, creams and liquids.

In Biologics

We’re providing transformative technologies and services to revolutionize biopharmaceutical manufacturing processes for all commercial cell lines – through a unique combination of high-yielding upstream technologies and process step-reducing downstream technologies. The result: We’re getting treatments for life-threatening diseases to market faster and more cost effectively.

In Microbial fermentation

DSM has more than 100 years’ experience in fermentation-based technologies. We cover many microorganisms through a multitude of products ranging from complex metabolites like anti-infectives, to bioactive proteins (enzymes and pharmaceutical proteins).

In Anti-Infectives

We are one of the world’s largest providers of antibiotic active ingredients based on penicillin. Our beta lactam-based anti-infectives combat deadly infectious diseases all over the world – to the tune of half a billion treatments.

Young female pharmacist with her arms crosedWe’re also one of the greenest producers. Our DSMPureActives™ brand is a family of active ingredients produced in such a way that energy consumption has been cut up to two-thirds; up to 90% less waste is produced and harmful emissions are cut by 50%.  But just as importantly, the purity of our DSMPureActives™ offers advantages for our direct customers who convert our active ingredients into finished dosage forms, which in turn help cure the infectious diseases of patients.

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