We know that your product development journey for Extracellular Matrices (ECMs) starts with improved patient healing. Our ECM technology offers guided tissue regeneration to help you achieve this by mimicking natural tissue and enabling cellular integration – in everything from wound care and soft tissue reconstruction, to orthopedic and cardiovascular applications.
10 years of commercial use.
Published in 40+ peer-reviewed journal articles globally.
30+ years of experience working with the world’s leading medical device and pharmaceutical companies.
Our biomimetic ECM scaffolds provide a naturally derived collagen structure, complemented by unique processing capabilities that maintain the natural properties of connective tissue (native growth factors, sugars, and proteins) - and help remove antigenic components.
Not only can we process a wide range of tissue sources and types for use in medical grade ECM scaffolds; our experts can combine our ECM materials with either our synthetic polymers or your own. In addition to all of this, we bring added peace of mind, through:
Our ECM sheet materials are ideal for soft tissue reconstruction. Their unique mechanical qualities also make them ideal for multiple applications.
We can easily modify our custom ECM forms to work smoothly with your existing processes and materials.
Our R&D experts can work with your tissues and processes through smooth production process transfers to co-create the ideal biologic scaffold.
How do we create the ideal biologic scaffold material? The key is a gentle process that maintains the natural integrity of the natural micro and macro structure of the biologic tissue. At the same time, this process removes antigenic components like cellular remnants, DNA, and phospholipids – all while maintaining levels of other important ECM components.*
Today, our ECM materials are being used to treat patients worldwide in everything from wound care, to dental barrier membranes, orthopedic reinforcement, and soft tissue reconstruction.
We create sustainable healthcare solutions that deliver tangible and valuable sustainability benefits to our partners – with no compromises on safety or performance.
*The effects of these components have not been evaluated clinically.
DSM’s extracellular matrices contain collagen, but due to their gentle and selective processing, they also contain native growth factors, elastin, and other extracellular components. Collagen is broken down and rebuilt to create customized forms; while ECM’s processing preserves the strength and features of the native tissue.
Our extracellular matrix is primarily available in sheet form; however, the process can be applied to many tissue types. This enables us to work closely with partners, providing customized solutions to meet their needs.
Looking for more information on how our ECM technology can help you tackle unmet needs?
We understand that medical product development can be a long, winding - and occasionally bumpy road. Rest assured that at DSM Biomedical, we have the proven experience, capabilities, and knowledge to support you every step of the way.
It starts with using a form-fit-function approach based on a comprehensive understanding of how the human body reacts to biomaterials following implantation. This in turn enables us to design materials that are compatible with the body’s physiology and help you develop finished products that can sustain, restore, and repair – all supported by applicable regulatory requirements.
Discover how we can partner with you to create innovative regenerative medicine and devices.
Our ECM experts are here to help.