Innovative biomaterial solutions for cardiovascular disease

Finding more effective ways to tackle heart disease is a major societal challenge that will almost certainly touch every one of us (either directly or indirectly) during our lifetime. With 50% of men and 30% of women estimated to develop coronary artery disease at some point during their lives1, it’s a challenge we are tackling every day with medical grade biomaterials and expertise - proven to help you to create safe, high-performing cardiovascular devices and therapies.

1  Sanchis-Gomar F, Perez-Quilis C, Leischik R, Lucia A. Epidemiology of coronary heart disease and acute coronary syndrome. Ann Transl Med. 2016 Jul;4(13):256.

We work with partners worldwide across the continuum of healthcare to co-create unique cardiovascular solutions that support patient healing – and bring progress to life



30+ years of experience in the cardiovascular market.



Every second a patient receives a medical device containing a DSM Biomedical solution.


Master Files

25 FDA Material Master Files available to support regulatory submissions. 

Getting to the heart of cardiovascular challenges

We see a cardiovascular market that is growing fast; and centered on improving both the positive clinical effects of heart surgery and recovery times for patients. At the same time, patients striving to manage cardiovascular conditions are demanding smaller, less intrusive and more comfortable devices. 

For our partners, the challenge is clear - creating more effective cardiovascular therapies and devices with greater durability, ease of implantation, and effectiveness while navigating the long regulatory path needed to get these products to market. Today, our experts are working to address all these challenges (and more).

Discover our integrated biomaterial portfolio for cardiovascular applications

Structural Heart

Biocompatible materials like our medical polyurethanes can help you improve the durability and overall effectiveness of structural heart solutions – including catheter-based therapies like heart valve repair and replacement.

This also extends to use in transcatheter heart valve replacement (aortic, mitral, and tricuspid), LAAO (Left Atrial Appendage Occlusion); and mitral/tricuspid valve repair (through clips or annuloplasty). 

We can also support you in enhancing minimally invasive procedures with the industry’s highest strength, lowest profile Ultra High Molecular Weight Polyethylene (UHMWPE) fibers for sutures and medical textiles.

Vascular Closure

For fast healing of puncture sites following vascular interventions, our fully resorbable collagen materials are an ideal choice. These naturally derived biomaterials are used for access vessel sealing post-catheterization (for example, in the SFA) to provide rapid hemostasis, thus lowering intraprocedural bleeding.

In fact, DSM Biomedical is a pioneer in this field, having created the Angio-Seal more than 25 years ago. Created from a trusted collagen source, it is available in multiple shapes and sizes, including a plug or patch. 

Interventional Cardiology

We know that creating differentiated solutions in this highly competitive market is paramount. Our advanced biomaterials for catheter-based therapies can help you achieve this.

For example, our hydrophilic lubricious coatings are ideal for both catheters and their various accessory devices, including guidewires and introducer sheaths used in procedures like cardiac ablation, coronary atherectomy, and intravascular imaging via IVUS or OCT. 

These materials are also a good choice for use in coronary and peripheral angioplasty and stenting; balloon valvuloplasty; and cardiac catheterization. In fact, our coating technology is particularly well suited for tortuous parts of the anatomy.

Finally, if you’re striving to achieve increased device miniaturization in delivery and retrieval catheters, our UHMWPE fiber portfolio is an ideal solution: it can be incorporated as a tendon or cable for mechanical steering.

Cardiac Assist Devices

In the drive to create less invasive cardiac assist devices that optimize cardiac function, we support you with a range of hemocompatible and durable biomaterials. These medical grade materials are ideal for multiple-component applications that require safe and effective long-term implantation in the body, including LVADs and other ventricular assist devices.

We also support further innovation in this application – for example through the creation of leadless digital technologies in headers, pumps, and coating electronics. The excellent processability of our medical polyurethanes enable the precision molding and coating of these parts.

An unrivaled biomaterials portfolio

We are proud to offer you a portfolio of customizable, combinable, and sustainable biomaterials that is unrivaled in the medical industry.

Visit our Knowledge Center

At DSM Biomedical we’ve built a wealth of knowledge in cardiovascular solutions.

Technical Resources

Looking for more information on how our biomaterial solutions for cardiovascular applications can help you tackle unmet needs?

Biomaterials for Bioprosthetic Heart Valves                                

Ulteeva Purity™ Brochure                              

ComfortCoat® Lubricious Hydrophilic Coating Datasheet  

Our cardiovascular team is here and ready to support you

Discover how our team can partner with you to co-create new cardiovascular solutions that can improve patient care.

Need expert assistance? 

Our cardiovascular experts are here to help.

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