The challenge of treating  wide ranging cardiovascular diseases requires specialized procedures and tools. Medical device manufacturers trust our innovative biomedical materials science solutions to help make their devices smaller, stronger and more durable to meet the growing needs of patients living longer lives.​

25

25 Master Files​
at FDA​

30+

Serving the market
for over 30 years

1M+

Each year, over 1 million cardiac/neuromodulation leads are implanted using DSM’s polyurethanes​

Examples of medical devices in which DSM biomaterials have been applied:

  • Cardiac assist devices, such as artificial hearts, pacemakers and ventricular assist devices
  • Central venous catheters​
  • Cerebral shunts​
  • Drug coated balloons​
  • Embolic protection filters​
  • Guidewires & introducer sheaths​
  • High-strength vascular sutures​
  • Intravascular imaging & pressure monitoring catheters​
  • Leads for pacemakers, Implantable cardiac defibrillators and CRT devices​
  • PTCA and PTA balloon catheters​
  • Resorbable and non-resorbable coatings for drug eluting stents​
  • Sternum closure​
  • Transcatheter heart valves and their delivery systems​
  • Vascular closure devices​

New pathways in heart valve disease treatment

Together, DSM and SAT are developing affordable, durable and minimally invasive replacement heart valves.

Strait Access Technologies (SAT) develops technologies to treat heart valve diseases. The company's focus on the complex requirements for devices suitable for younger patients with rheumatic heart disease (RHD) has delivered breakthrough solutions. These new approaches also promise benefits for older patients with degenerative heart valve conditions. Professor Peter Zilla, CEO & Medical Director, discusses SAT’s collaboration with DSM on innovative replacement heart valves.

In 2018, the World Health Organization declared RHD a global health priority. RHD is a major health concern in emerging economies, affecting similar numbers of people as HIV. Our products treat RHD — a potentially fatal condition that can develop from lack of access to antibiotics.

DSM's R&D capabilities and advanced biomaterials expertise have allowed SAT to produce a ground-breaking

product with compelling commercial prospects. SAT’s new heart valves are made with polymeric leaflets composed of DSM's CarboSil® Thermoplastic Silicone-Polycarbonate-Urethane (TSPCU). CarboSil® TSPCU gives the valves durability and also dispenses with the need for anticoagulants. Traditional replacement heart valves either require the patient to take anticoagulants on a daily basis, with potentially negative side-effects, or else are of limited durability, especially in the case of younger patients.

These products are still in the development and testing phase but have already received strong encouragement from non-governmental organizations such as the World Heart Federation. They will be launched on receipt of regulatory approval.

DSM technologies serving this market​

  • Coatings

    Hydrophilic coatings that provide industry-leading process control and process optimization.

  • Collagen

    Create versatile scaffold solutions for tissue repair, cell proliferation, hemostasis and carriers for your APIs.

  • Drug delivery

    Discover our implantable drug delivery systems made of bioresorbable polymers that release precise quantities of therapeutic agents gradually over time.

  • Polyethylenes

    Discover how the strongest medical grade fiber in the world can be used to enhance your product designs and create new innovative solutions.

  • Polyurethanes

    Explore our wide array of polyurethanes, how they can be adapted to your product designs and how we can create innovative solutions that add value to your portfolio.

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  • Our products

    DSM portfolio of innovative biomedical materials and process manufacturing technologies: Biomedical Polyethylenes, Biomedical polyurethanes, Collagen Technology, Device Development, and Extracellular Matrix (ECM) Technology. Learn more.

  • The markets we serve

    DSM Biomedical offers the broadest portfolio of biomedical materials and manufacturing across market applications, including orthopedics, ophthalmology, neurology, cardiology, diabetes, wound, and continence care.

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