AGP management includes changes in production and feed formulation to support a balance of the bird’s microbiome while also regularly monitoring the flock for any health or nutrition changes. Prebiotics, probiotics, or together as a synbiotic support competitive exclusion and intestinal integrity which reduces the incidence of pathogen colonization. A novel precision- biotic redirects protein away from opportunistic pathogens and towards productive microbial protein metabolism. Reducing bacterial cell debris which is blocking nutrient absorption in the gut will support optimal feed efficiency. Further support can be provided with optimum vitamins that have higher bioavailability and reducing the risk of mycotoxins in the feed.