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Niacin (Vitamin B3)

dsm-firmenich ESSENTIAL PRODUCTS

B group vitamins act as coenzymes on different metabolic pathways and, in many biochemical reactions multiple B-group vitamins are involved at the same time. Their presence is fundamental for the normal functioning of the organism.

Niacin: the anti-pellagra factor 

The two forms of niacin or vitamin B3, nicotinic acid and nicotinamide, are functional parts of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), involved in the cellular respiration processes. About 200 enzymes require NAD or NADP. NAD is mainly involved in reactions that generate energy in the tissue through the degradation of carbohydrates, proteins and fats. NADP is involved in the biosynsthesis of fatty acids and cholesterol.

For more information on dsm-firmenich Vitamin Supplementation Guidelines.

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dsm-firmenich ProductContent (min.)Formulation TechnologyApplication
ROVIMIX® Niacin99.5% (995 g/kg)Fine crystalline powderMash, Pellet, Expansion, Extrusion
ROVIMIX® Niacinamide99.5% (995 g/kg)Fine crystalline powderMash, Pellet, Expansion, Extrusion, Milk replacer/Water

Selected species

Main functions:

  • Coenzyme (active forms NAD and NADP) in amino acid, fat and carbohydrate metabolism
  • Required for optimum tissue integrity, particularly for the skin, the gastrointestinal tract and the nervous system

Deficiency symptoms:

  • Nervous system disorders
  • Inflammation and ulcers of mucous membranes
  • Reduced growth and feed efficiency
  • Lameness in young birds
  • Reduced feathering
  • Reduced egg production and hatchability

Main functions:

  • Coenzyme (active forms NAD and NADP) in amino acids, fats and carbohydrates metabolism
  • Required for optimum tissue integrity, particularly for the skin, the gastrointestinal tract and the nervous system

Deficiency symptoms:

  • Nervous system disorders
  • Inflammation and ulcers of mucous membranes
  • Reduced growth and feed efficiency
  • Dermatitis (pellagra), hair loss 
  • Ulcerative necrotic lesions of the large intestine, diarrhoea
  • Reduced reproductive performance

Main functions:

  • Coenzyme (active forms NAD and NADP) in aminoacids, fats and carbohydrates metabolism
  • Required for optimum tissue integrity, particularly for the skin, the gastrointestinal tract and the nervous system

Deficiency symptoms:

  • Nervous system disorders
  • Skin and hair disorders
  • Inflammation and ulcers of mucous membranes
  • Ulcerative necrotic lesions of the large intestine
  • Reduced milk yield and feed efficiency
  • Increased risk of ketosis
  • Reduced reproductive performance

Main functions:

  • Coenzyme, in the active forms NAD and NADP, in aminoacids, fat and carbohydrate metabolism
  • Involved in glycolysis, citric acid cycle, oxidation of fatty acids and fatty acids synthesis and gluconeogenesis

Deficiency symptoms:

  • Nervous system disorders
  • Deformities (spinal, jaws)
  • Edema
  • Growth retardation
  • Hematological index changes
  • Hemorrhage
  • Lesions
  • Lethargy
  • Loss of appetite up to anorexia
  • Muscle dystrophy
  • Inflammation and ulcers of mucous membranes
  • Increase of disease in stress conditions
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