SYN®-AKE Safety Safety Data Sheet
SAFETY DATA SHEET for the peptide ingredient SYN®-AKE according to Regulation (EC) No. 1907/2006.
SYN®-AKE is a small synthetic peptide that helps reduce the appearance of wrinkles and laughter lines – fast.
As our skin gets older so the number of expression and laughter lines increases, along with crow’s feet and forehead wrinkles. SYN®-AKE enables the face to relax, reducing wrinkles but without losing the ability to help people express themselves. It’s fast acting, long lasting and fully reversible.
Measurement of the smoothing (Ra) and anti-wrinkle effect (Rz and Rt) of SYN®-AKE (4%) measured on the crow’s feet after 28 days.
With SYN®-AKE the depth of wrinkles is visibly reduced, and an overall smoother and more even skin surface appears.
SYN®-AKE is based on a patented mechanism. It mimics the essential amino acid sequence of the Waglerin-1 functionality.
Its effect focuses on an immediate and lasting relaxation of mimic wrinkles. In vitro the peptide cosmetic ingredient is considered as an antagonist at the muscular nicotinic acetylcholine receptor (mnAChR). As the muscular nicotinic ACh receptors are reversibly blocked, the ion channel remains closed. There is no uptake of Na+ and the muscle cells stay relaxed. The transmission of nerve impulses to the muscles is inhibited and facial muscles are relaxed.